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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ATI 2341/5795/1/1 mg
产品编号:5795/1
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ATI 2341/5795/1/1 mg
商品介绍
Description:CXCR4allostericagoNIST
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CXCR4allostericagonist(EC50=194nM).InduceschemotaxisinCXCR4-expressingcellsinvitro.Mobilizespolymorphonuclearneutrophils(PMNs)andhematopoieticstemandProgenitorcells(HSPCs)frombonemarrownicheinvivo.ExhibitsbiasedsignalingtowardsGiproteinsoverG13andβ-arrestin.

TechnicalData

M.Wt2256.82
FormulaC104H178N26O25S2
SequenceMGYQKKLRSMTDKYRL

(Modifications:Met-1=N-terminalPalmitoyl)

StorageStoreat-20°C
CASNumber1337878-62-2
PubChemID101961246
InChIKeyYMLOFEANRZSEGQ-QNHYGVTPSA-N
SmilesCCCCCCCCCCCCCCCC(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight2256.82.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.44mL2.22mL4.43mL
5mM0.09mL0.44mL0.89mL
10mM0.04mL0.22mL0.44mL
50mM0.01mL0.04mL0.09mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet