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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AM 114/2564/10/10 mg
产品编号:2564/10
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AM 114/2564/10/10 mg
商品介绍
Description:20Sproteasomeinhibitor
ChemicalName:3,5-Bis-[benzylidene-4-boronicacid]-1-methylpiperidin-4-one
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofthechymotrypsin-likeactivityofthe20Sproteasome(IC50~1μM).Displaysanticanceractivity;inhibitscellgrowthinhumancoloncancerHCT116p53+/+cells(IC50=1.49μM).

LicensingInformation

SoldwiththepermissionofJohnsHopkinsUniversity

TechnicalData

M.Wt377.01
FormulaC20H21B2NO5
StorageStoreat+4°C
Purity≥97%(HPLC)
CASNumber856849-35-9
PubChemID11639443
InChIKeySRPIKXGUPAKTIZ-OTYYAQKOSA-N
SmilesO=C(/C(CN(C)C3)=C/C2=CC=C(B(O)O)C=C2)/C3=C/C1=CC=C(B(O)O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO3.7710

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight377.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.65mL13.26mL26.52mL
5mM0.53mL2.65mL5.3mL
10mM0.27mL1.33mL2.65mL
50mM0.05mL0.27mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet