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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ASP 7663/5178/10/10 mg
产品编号:5178/10
市  场 价:¥3700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$185.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ASP 7663/5178/10/10 mg
商品介绍
Description:SelectiveTRPA1activator
ChemicalName:(2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]aceticacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveTRPA1activator(EC50valuesare~0.5μMinhuman,mouseandrat).Displayslittleornoaffinityatmorethan60otherrelatedreceptors,channelsandenzymes.Stimulates5-HTreleasefromQGP-1cells.ExhibitsanaBDominalanalgesiceffectinvivo.Orallybioavailable.

TechnicalData

M.Wt263.26
FormulaC14H14FNO3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1190217-35-6
PubChemID44232532
InChIKeyRCVZUIGCNAAMIC-UXBLZVDNSA-N
SmilesO=C2/C(C1=CC=CC(F)=C1N2CC(C)C)=C/C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO26.33100
ethanol26.33100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight263.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.8mL18.99mL37.99mL
5mM0.76mL3.8mL7.6mL
10mM0.38mL1.9mL3.8mL
50mM0.08mL0.38mL0.76mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet