请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ZAPA sulfate/0180/50/50 mg
产品编号:0180/50
市  场 价:¥10700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$535.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ZAPA sulfate/0180/50/50 mg
商品介绍
Description: Agonist at 'low affinity' GABAA receptor. More potent than GABA/muscimol
Chemical Name: (Z)-3-[(Aminoiminomethyl)thio]prop-2-enoic acid sulfate
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

More potent than either GABA or muscimol as an agonist at low affinity GABAA receptors and is thus a useful ligand to investigate GABA receptors linked to benzodiazepine receptors. Also a GABAA-ρ receptor antagonist.

Technical Data

M. Wt 244.24
Formula C4H6N2O2S.H2SO4
Storage Store at RT
CAS Number 371962-01-5
PubChem ID 90479730
InChI Key UWVNHPNVOMFDHW-ODZAUARKSA-N
Smiles OS(O)(=O)=O.NC(=N)SC=C/C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

SolubilitySoluble to 10 mM in water

Preparing Stock Solutions

The following data is based on the product molecular weight 244.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.09 mL 20.47 mL 40.94 mL
5 mM 0.82 mL 4.09 mL 8.19 mL
10 mM 0.41 mL 2.05 mL 4.09 mL
50 mM 0.08 mL 0.41 mL 0.82 mL

Product Datasheets

Certificate of Analysis / Product Datasheet
Safety Datasheet

References

References are publications that support the products' biological activity.

Allan et al (1986) Isothiouronium compounds as γ-aminobutyric acid agonists. Br.J.Pharmacol. 88 379 PMID: 3015310

Holden-Dye and Walker (1988) ZAPA, (Z)-3-[(aminoiminomethyl)thio]-2-propenoic acid hydrochloride, a potent agonist at GABA-receptors on the Ascaris muscle cell. Br.J.Pharmacol. 95 3 PMID: 2851353

Johnston (1996) GABAC receptors: relatively simple transmitter-gated ion channels? TiPS 17 319 PMID: 8885697


Keywords: ZAPA sulfate, supplier, GABAC, antagonists, agonists, low, affinity, GABAA, receptors, GABAA, Receptors, GABAA-rho, Receptors, GABAA, Receptors, Tocris Bioscience

品牌介绍

Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌,其产品也广为各大药厂、大学、研究机构,超过五万名科学研究者所采用。 目前,產品內容已超過一千六百種以上,並每年持續不斷的增加新的產品。目前,产品内容已超过一千六百种以上,并每年持续不断的增加新的产品。

Tocris bioscience是位于英国布里斯托尔(Bristol)的高品质试剂提供商,共有2000多种产品,主要集中在神经科学和信号传导领域,产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等,主要产品包括GPCR ligands,神经传递素,离子通道调控剂,信号通路抑制剂等,这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者,其生产的影响神经系统的化学物质被多次引用,这些物质很多都来自Jeff Watkins(Tocris 的创立人)在Bristol大学原创性的研究工作。

Tocris Bioscience has been working with scientists for over 30 years to provide the life science community with the latest and most innovative research tools available. We understand the need for researchers to trust their research reagents, which is why we are committed to supplying our customers with the highest quality product available, so you can publish with confidence. To find out more about Tocris, please click on the tiles below.

Tocris is part of the life science division of Bio-Techne, which also includes the best in class brands R&D Systems, Novus Biologicals, ProteinSimple and Advanced Cell Diagnostics. Bio-Techne has united these brands to provide researchers with a full portfolio of research reagents, assays and protein platforms. For more information on Bio-Techne and its brands, please visit bio-techne.com.


自营商城图标
厂家直采
全球直采 正品优价
正品保障图标
正品保障
厂家直发 有线跟踪
解放采购图标
正规清关
CIF100%正规报关,提供发票
及时交付图标
及时交付
限时必达 不达必赔