Long-acting5-HT2Areceptorantagonist;inhibitsvasoconstrictionandblocksplateletaggregation.Prolongsclottingtimeinaratmodelofthrombusformation;ameliorateslaurate-inducedperipheralvascularlesionsinrodents.
AT1015isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 492.05 |
| Formula | C29H33N3O2.HCl |
| Storage | Storeat+4°C |
| Purity | ≥97%(HPLC) |
| CASNumber | 190508-50-0 |
| PubChemID | 9805663 |
| InChIKey | YZHGXYNLMHGNJZ-UHFFFAOYSA-N |
| Smiles | O=C(C5CCN(C=O)CC5)NCCN(CC3)CC/C3=C1C(C=CC=C4)=C4C=CC2=C1C=CC=C2.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 49.2 | 100 | |
| water | 49.2 | 100 |
Thefollowingdataisbasedontheproductmolecularweight492.05.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.03mL | 10.16mL | 20.32mL |
| 5mM | 0.41mL | 2.03mL | 4.06mL |
| 10mM | 0.2mL | 1.02mL | 2.03mL |
| 50mM | 0.04mL | 0.2mL | 0.41mL |



