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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AS 2034178/5035/50/50 mg
产品编号:5035/50
市  场 价:¥15300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$765.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AS 2034178/5035/50/50 mg
商品介绍
Description:SelectiveFFA1(GPR40)agoNIST
ChemicalName:2-Fluoro-4-[[[1,2,3,4-Tetrahydro-1-(2-phenoxyethyl)-5-quinolinyl]methyl]amino]benzenepropanoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivefreefattyacidreceptor1(FFA1/GPR40)agonist.ExhibitsselectivityforGPR40overGPR41,GPR43,GPR119,GPR120andPPARγ.Inducesglucose-dependentinsulinsecretioninpancreaticMIN6cellsandinvivo.Enhancesinsulinsensitivityinatype2diabetesmodelinvivo.Orallyavailable.

CompoundLibraries

AS2034178isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt448.53
FormulaC27H29FN2O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1030846-42-4
PubChemID24808572
InChIKeyVENOXIKBBUVHRY-UHFFFAOYSA-N
SmilesFC1=C(CCC(O)=O)C=CC(NCC2=C(CCCN3CCOC4=CC=CC=C4)C3=CC=C2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.4350
ethanol8.9720

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight448.53.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.23mL11.15mL22.3mL
5mM0.45mL2.23mL4.46mL
10mM0.22mL1.11mL2.23mL
50mM0.04mL0.22mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet