GPR119receptoragonist(EC50=2.5μMinHEK293cellsexpressinghumanGPR119).Enhancesinsulinsecretionstimulatedbyglucoseinvivo.Stimulatesproglucagongenepromoteractvity.Orallyavailable.
AS1269574isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 308.17 |
Formula | C13H14BrN3O |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 330981-72-1 |
PubChemID | 5332859 |
InChIKey | DUKPGOOUJNUIOI-UHFFFAOYSA-N |
Smiles | BrC(C=C2)=CC=C2C1=NC(NCCO)=CC(C)=N1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 30.82 | 100 | |
ethanol | 30.82 | 100 |
Thefollowingdataisbasedontheproductmolecularweight308.17.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.24mL | 16.22mL | 32.45mL |
5mM | 0.65mL | 3.24mL | 6.49mL |
10mM | 0.32mL | 1.62mL | 3.24mL |
50mM | 0.06mL | 0.32mL | 0.65mL |