FAAH-likeanandamidetransporter(FLAT)inhibitor(IC50=1.8μM);cytosolicvariantofFAAH-1thatbindsanandamide.Attenuatesanandamideinternalizationanddeactivationinvitroandinvivorespectively.ExhibitsanalgesiceffectsinrodentmodelsofCB1-mediatednociceptiveandinflammatorypain.
M.Wt | 432.47 |
Formula | C27H20N4O2 |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 488793-85-7 |
PubChemID | 24802717 |
InChIKey | YNADXFWEXJTQSZ-UHFFFAOYSA-N |
Smiles | OC(C=C4)=CC=C4C2=NN=C(NC3=CC=C(C(NC5=CC=CC=C5)=O)C=C3)C1=CC=CC=C12 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 43.25 | 100 | |
ethanol | 8.65 | 20 |
Thefollowingdataisbasedontheproductmolecularweight432.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.31mL | 11.56mL | 23.12mL |
5mM | 0.46mL | 2.31mL | 4.62mL |
10mM | 0.23mL | 1.16mL | 2.31mL |
50mM | 0.05mL | 0.23mL | 0.46mL |