Selectiveα2Badrenoceptorantagonist(pKDvaluesare8.8,6.7and6.4atα2B,α2A,andα2Dreceptorsrespectively).Alsoavailableaspartoftheα2-AdrenoceptorTocriset™.
SoldwiththepermissionofBoehringerIngelheimGmbH
| M.Wt | 480.43 |
| Formula | C24H29N3O3.2HCl |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 55974-42-0 |
| PubChemID | 10345075 |
| InChIKey | SAJKHRHHDGSJEZ-UHFFFAOYSA-N |
| Smiles | Cl.Cl.COC1=CC=CC=C1N1CCN(CCN2C(=O)C3=C(C=CC=C3)C(C)(C)C2=O)CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 48.04 | 100 | |
| water | 48.04 | 100 |
Thefollowingdataisbasedontheproductmolecularweight480.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.08mL | 10.41mL | 20.81mL |
| 5mM | 0.42mL | 2.08mL | 4.16mL |
| 10mM | 0.21mL | 1.04mL | 2.08mL |
| 50mM | 0.04mL | 0.21mL | 0.42mL |



