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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AR-C 102222/3969/50/50 mg
产品编号:3969/50
市  场 价:¥18500.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$925.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AR-C 102222/3969/50/50 mg
商品介绍
Description:SelectiveiNOSinhibitor
ChemicalName:5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrilehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InducIBLenitricoxidesynthase(iNOS)inhibitor;selectiveforiNOSovereNOS(IC50valuesare0.037and>100μMforiNOSandeNOSrespectively).Exhibitsantinociceptiveandanti-inflammatoryactivityinrodentpainmodels.

LicensingInformation

SoldwiththepermissionofAstraZenecaUKLtd.

TechnicalData

M.Wt418.83
FormulaC19H16F2N6O.HCl
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber253771-21-0
PubChemID21192822
InChIKeyFJFMOBYDHGJDGV-UHFFFAOYSA-N
SmilesO=C(C4=CC=C(C#N)N=C4)N(CC3)CCC23N=C(N)C1=C(F)C=CC(F)=C1N2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO41.86100
water10.4725

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight418.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.39mL11.94mL23.88mL
5mM0.48mL2.39mL4.78mL
10mM0.24mL1.19mL2.39mL
50mM0.05mL0.24mL0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet