请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/APcK 110/3704/50/50 mg
产品编号:3704/50
市  场 价:¥16900.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>激酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$845.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/APcK 110/3704/50/50 mg
商品介绍
Description:KITinhibitor
ChemicalName:6-(3,5-Dimethoxyphenyl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

KITinhibitor;inhibitsphosphorylationofKIT,STAT3,STAT5andAkt.SuppressesproliferationofOCI/AML3cells(IC50=175nM).Caspase-dependantapoptosisinducer.

CompoundLibraries

APcK110isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxI.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt349.36
FormulaC20H16FN3O2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1001083-74-4
PubChemID24786010
InChIKeyCAMGZGMEPKFVMF-UHFFFAOYSA-N
SmilesFC(C=C3)=CC=C3C1=NNC2=C1C=CC(C4=CC(OC)=CC(OC)=C4)=N2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO34.94100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight349.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.86mL14.31mL28.62mL
5mM0.57mL2.86mL5.72mL
10mM0.29mL1.43mL2.86mL
50mM0.06mL0.29mL0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet