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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/APY 29/4865/10/10 mg
产品编号:4865/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/APY 29/4865/10/10 mg
商品介绍
Description:InhibitsIRE1αautophosphorylation;activatesIRE1αendoribonucleaseactivity
ChemicalName:N2-1H-Benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AllostericmodulatorofIRE1α.InhibitsIRE1αautophosphorylation(IC50=280nM)andactivatesIRE1αribonucleaseactivity.

CompoundLibraries

APY29isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt332.36
FormulaC17H16N8
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1216665-49-4
PubChemID42627755
InChIKeyWJNBSTLIALIIEW-UHFFFAOYSA-N
SmilesC1(NC2=CC(NC=N3)=C3C=C2)=NC=CC(NC4=CC(C5CC5)=NN4)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.HCl16.6250
DMSO33.24100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight332.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.01mL15.04mL30.09mL
5mM0.6mL3.01mL6.02mL
10mM0.3mL1.5mL3.01mL
50mM0.06mL0.3mL0.6mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet