请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AP 811/5498/1/1 mg
产品编号:5498/1
市  场 价:¥4700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$235.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AP 811/5498/1/1 mg
商品介绍
Description:Highaffinity,selectiveNPR3antagoNIST
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highaffinity,selectiveANPclearancereceptor(NPR3)antagonist(Ki=0.45nM).Exhibits>20,000-foldselectivityforNPR3overNPR1.InhibitsANP-stimulatedNa+/K+pumpactivityinrabbitventricularcardiomyocytesinvitro.AlsoblocksproliferationofrodentneonatalcardiomyocytesseenatlowANPconcentrationsinvitro.

TechnicalData

M.Wt915.1
FormulaC46H66N12O8
SequenceRIDR

(Modifications:Arg-1=N2-[4-(2-Naphthoylamino)phenylacetyl],Arg-4=C-terminal(S)-2-methylbutylamide)

StorageStoreat-20°C
CASNumber124833-45-0
PubChemID44301714
InChIKeyUNMJSSQZDQBGDS-OCFLPWLCSA-N
SmilesCC[C@H](C)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CC1=CC=C(NC(=O)C2=CC3=C(C=CC=C3)C=C2)C=C1)[C@@H](C)CC

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight915.1.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.09mL5.46mL10.93mL
5mM0.22mL1.09mL2.19mL
10mM0.11mL0.55mL1.09mL
50mM0.02mL0.11mL0.22mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet