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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AP 18/3296/10/10 mg
产品编号:3296/10
市  场 价:¥2580.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AP 18/3296/10/10 mg
商品介绍
Description:ReversIBLeTRPA1channelblocker
ChemicalName:4-(4-Chlorophenyl)-3-methyl-3-buten-2-oneoxime
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ReversibleTRPA1channelblocker(IC50valuesare3.1and4.5μMathumanandmouseTRPA1respectively).Blockscinnameldehyde-inducedbutnotcapsaicin-inducednociceptionandreversesmechanicalhyperalgesiainvivo.AlsoblocksTRPA1poredilation(IC50=10.3μMfortheinhibitionofYo-Prouptake).

CompoundLibraries

AP18isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt209.67
FormulaC11H12ClNO
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber55224-94-7
PubChemID9584673
InChIKeyMHTJEUOFLVQMCL-NJHPPEEMSA-N
SmilesClC1=CC=C(/C=C(C)/C(C)=N/O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO20.97100
ethanol20.97100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight209.67.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.77mL23.85mL47.69mL
5mM0.95mL4.77mL9.54mL
10mM0.48mL2.38mL4.77mL
50mM0.1mL0.48mL0.95mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet