Cell-permeablecAMPanalog;actsasacompetitiveantagonistofcAMP-inducedactivationofPKA(IC50=11-16μM)byinteractingwithcAMPbindingsitesontheregulatorysubunits.Resistanttohydrolysisbyphosphodiesterases.EnantiomercAMPS-Sp,triethylammoniumsalt(Cat.No.1333)alsoavailable.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight446.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.