Selective5-HTantagonist,whichbindsto5-HT2sitesaspotentlyasspiperonebuthasloweraffinityfor5-HT2Creceptors.AlsoahighaffinityD2receptorantagonist(Ki=3nM).Lacksthedisruptiveeffectofspiperoneonanimalbehavior.
M.Wt | 383.46 |
Formula | C22H26FN3O2 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 510-74-7 |
PubChemID | 68186 |
InChIKey | FJUKDAZEABGEIH-UHFFFAOYSA-N |
Smiles | FC(C=C4)=CC=C4OCCCN1CCC2(N(C3=CC=CC=C3)CNC2=O)CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 28.76 | 75 | |
ethanol | 1.92 | 5mMwithgentlewarming |
Thefollowingdataisbasedontheproductmolecularweight383.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.61mL | 13.04mL | 26.08mL |
5mM | 0.52mL | 2.61mL | 5.22mL |
10mM | 0.26mL | 1.3mL | 2.61mL |
50mM | 0.05mL | 0.26mL | 0.52mL |