请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AMG 837 hemicalcium salt/6082/50/50 mg
产品编号:6082/50
市  场 价:¥15900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$795.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AMG 837 hemicalcium salt/6082/50/50 mg
商品介绍
Description:Potentfreefattyacidreceptor1(FFA1/GPR40)partialagoNIST
ChemicalName:(βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoicacidhemicalciumsalt
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentfreefattyacidreceptor1(FFA1/GPR40)partialagonist(EC50valuesare13.5,22.6and31.7nMathuman,mouseandratreceptors,respectively).InteractsallostericallywithfullFFA1agonistDocosahexaenoicacid(Cat.No.3687).Potentiatesglucose-dependentstimulationofinsulininvivo.Antidiabetic.

TechnicalData

M.Wt457.47
FormulaC26H20F3O3.½Ca
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1291087-14-3
PubChemID46854655
InChIKeyWCZAHGONZBHQSA-UHFFFAOYSA-L
SmilesCC#C[C@H](C1=CC=C(C=C1)OCC2=CC=CC(C3=CC=C(C(F)(F)F)C=C3)=C2)CC([O-])=O.CC#C[C@H](C4=CC=C(C=C4)OCC5=CC=CC(C6=CC=C(C(F)(F)F)C=C6)=C5)CC([O-])=O.[Ca+2]

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO45.75100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight457.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.19mL10.93mL21.86mL
5mM0.44mL2.19mL4.37mL
10mM0.22mL1.09mL2.19mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet