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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AMD 3465 hexahydrobromide/4179/10/10 mg
产品编号:4179/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AMD 3465 hexahydrobromide/4179/10/10 mg
商品介绍
Description:PotentandselectiveCXCR4antagoNIST
ChemicalName:N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanaminehexahydrobromide
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectiveCXCR4antagonist;exhibits8-foldhigheraffinitythanAMD3100(Cat.No.3299).InhibitsSDF-1α-ligandbinding(Ki=41.7nM).PotentlyinhibitsHIVcellentryinvitro;causesleukocytosisandmobilizeshaematopoieticstemcellsinvivo.

CompoundLibraries

AMD3465hexahydrobromideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt896.07
FormulaC24H38N6.6HBr
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber185991-07-5
PubChemID9897616
InChIKeyARHBIBDGWDRBJH-UHFFFAOYSA-N
SmilesC1(CN3CCCNCCNCCCNCC3)=CC=C(CNCC2=NC=CC=C2)C=C1.Br.Br.Br.Br.Br.Br

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.425
water44.850

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight896.07.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.12mL5.58mL11.16mL
5mM0.22mL1.12mL2.23mL
10mM0.11mL0.56mL1.12mL
50mM0.02mL0.11mL0.22mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet