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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AM 580/0760/10/10 mg
产品编号:0760/10
市  场 价:¥3100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$155.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AM 580/0760/10/10 mg
商品介绍
Description:Retinoicacidanalog;RARαagoNIST
ChemicalName:4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AnanalogofretinoicacidthatactsasaselectiveRARαagonist(EC50valuesare0.3,8.6and13nMforRARα,RARβandRARγrespectively).SignificantlyinducesIL-4,IL-5andIL-13andinhibitsIL-12andIFNγsynthesis,andinducescelldifferentiationwithover7timestheactivityofretinoicacidinvitro.

CompoundLibraries

AM580isalsoofferedaspartoftheTocriscreenPlusandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt351.44
FormulaC22H25NO3
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber102121-60-8
PubChemID2126
InChIKeySZWKGOZKRMMLAJ-UHFFFAOYSA-N
SmilesCC1(C)CCC(C)(C)C2=CC(=CC=C12)C(=O)NC1=CC=C(C=C1)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO17.5750
ethanol35.14100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight351.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.85mL14.23mL28.45mL
5mM0.57mL2.85mL5.69mL
10mM0.28mL1.42mL2.85mL
50mM0.06mL0.28mL0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet