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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AM 4668/5789/50/50 mg
产品编号:5789/50
市  场 价:¥15900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$795.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AM 4668/5789/50/50 mg
商品介绍
Description:PotentFFA1(GPR40)agoNIST
ChemicalName:(βS)-β-[4-[[4-Methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methoxy]phenyl)-3-isoxazolepropanoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentFFA1(GPR40)agonist(EC50=3.6nMinanIP3assayinGPR40transfectedA9cells).Inhibitsinsulinsecretionfromisolatedpancreaticislets.Reducesbloodglucoselevelsfollowingoralglucosechallengeinmice.Orallybioavailable.

TechnicalData

M.Wt488.48
FormulaC24H19F3O4S
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1011531-27-3
PubChemID24897670
InChIKeyBMLGZNVPWRUVNM-IBGZPJMESA-N
SmilesCC1=C(COC2=CC=C(C=C2)[C@H](CC(O)=O)C2=NOC=C2)SC(=N1)C1=CC=C(C=C1)C(F)(F)F

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO48.85100
ethanol48.85100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight488.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.05mL10.24mL20.47mL
5mM0.41mL2.05mL4.09mL
10mM0.2mL1.02mL2.05mL
50mM0.04mL0.2mL0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet