ArelativelypotentandselectiveantagonistofgroupImetabotropicglutamatereceptors(mGlu1a),havingnoeffectongroupII(mGlu2)orgroupIII(mGlu4)receptorsexpressedindividuallyinbabyhamsterkidneycells.Hasnoeffectonionotropicglutamatereceptors.Centrallyactivefollowingsystemicadministrationinvivo.
M.Wt | 221.21 |
Formula | C11H11NO4 |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 168560-79-0 |
PubChemID | 2071 |
InChIKey | LSTPKMWNRWCNLS-UHFFFAOYSA-N |
Smiles | NC2(C(O)=O)C1=CC=C(C(O)=O)C=C1CC2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
1.1eq.NaOH | 22.12 | 100 |
Thefollowingdataisbasedontheproductmolecularweight221.21.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 4.52mL | 22.6mL | 45.21mL |
5mM | 0.9mL | 4.52mL | 9.04mL |
10mM | 0.45mL | 2.26mL | 4.52mL |
50mM | 0.09mL | 0.45mL | 0.9mL |