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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AH 7614/5256/10/10 mg
产品编号:5256/10
市  场 价:¥1980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$99.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AH 7614/5256/10/10 mg
商品介绍
Description:SelectiveFFA4(GPR120)antagoNIST
ChemicalName:4-Methyl-N-9H-xanthen-9-yl-benzenesulfonamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivefreefattyacidreceptor4(FFA4/GPR120)antagonist(pIC50valuesare7.1and<4.6forhumanFFA4andFFA1receptorsrespectively).InhibitslinoleicacidandGSK137647A-inducedintracellularcalciumaccumulationinU2OSosteosarcomacellsexpressingtheFFA4receptor.

LicensingInformation

SoldforresearchpurposesunderagreementfromGlaxoSmithKline

CompoundLibraries

AH7614isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt351.42
FormulaC20H17NO3S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber6326-06-3
PubChemID233085
InChIKeyOZCQEUZTOAAWDK-UHFFFAOYSA-N
SmilesCC(C=C4)=CC=C4S(NC2C3=C(C=CC=C3)OC1=CC=CC=C12)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO35.14100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight351.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.85mL14.23mL28.46mL
5mM0.57mL2.85mL5.69mL
10mM0.28mL1.42mL2.85mL
50mM0.06mL0.28mL0.57mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet