Selectivefreefattyacidreceptor4(FFA4/GPR120)antagonist(pIC50valuesare7.1and<4.6forhumanFFA4andFFA1receptorsrespectively).InhibitslinoleicacidandGSK137647A-inducedintracellularcalciumaccumulationinU2OSosteosarcomacellsexpressingtheFFA4receptor.
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AH7614isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 351.42 |
Formula | C20H17NO3S |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 6326-06-3 |
PubChemID | 233085 |
InChIKey | OZCQEUZTOAAWDK-UHFFFAOYSA-N |
Smiles | CC(C=C4)=CC=C4S(NC2C3=C(C=CC=C3)OC1=CC=CC=C12)(=O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 35.14 | 100 |
Thefollowingdataisbasedontheproductmolecularweight351.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.85mL | 14.23mL | 28.46mL |
5mM | 0.57mL | 2.85mL | 5.69mL |
10mM | 0.28mL | 1.42mL | 2.85mL |
50mM | 0.06mL | 0.28mL | 0.57mL |