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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/AF-DX 116/1105/10/10 mg
产品编号:1105/10
市  场 价:¥3100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$155.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/AF-DX 116/1105/10/10 mg
商品介绍
Description:SelectiveM2antagoNIST
AlternativeNames:Otenzepad
ChemicalName:11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveM2muscarinicreceptorantagonist.Kivaluesare64,417,786,211and5130nMforhumanrecombinantM2,M1,M3,M4andM5muscarinicreceptors,respectively.

LicensingInformation

SoldwiththepermissionofBoehringerIngelheimGmbH

CompoundLibraries

AF-DX116isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt421.54
FormulaC24H31N5O2
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber102394-31-0
PubChemID107867
InChIKeyUBRKDAVQCKZSPO-UHFFFAOYSA-N
SmilesCCN(CC)CC1CCCCN1CC(=O)N1C2=C(C=CC=C2)C(=O)NC2=CC=CN=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO10.5425mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight421.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.37mL11.86mL23.72mL
5mM0.47mL2.37mL4.74mL
10mM0.24mL1.19mL2.37mL
50mM0.05mL0.24mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet