Potent,isoform-selectiveRARβ2receptoragonist(pEC50valuesare6.9,5.7and5.6atRARβ2,RARβ1andRARαrespectively)thatdisplays100-foldselectivityversusotherretinoidreceptors.InhibitsproliferationofthebreastcancercelllineMCF-7.
AC55649isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight310.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.