Tocris/AC 5216/5281/10/10 mg,Tocris,,Tocris,Tocris Bioscience,Tocris美元价/进货价 Tocris信号通路抑制剂,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Tocris/AC 5216/5281/10/10 mg

产品编号：5281/10

市场价：¥3300.00

场地：美国(厂家直采)

产品分类：生化试剂>生物分子>转运体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$165.00

品牌： Tocris

公司：Tocris Bioscience

公司分类：

商品介绍

Description:SelectiveTSPOligand

AlternativeNames:XBD173

ChemicalName:N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Ligandoftranslocatorprotein(TSPO,peripheralbenzodiazepinereceptor).ExhibitshighaffinityforTSPOinratwholebrain(K_i=0.297nM),andhighpotencyagainsthumanandratglialTSPO(IC₅₀valuesare2.73and3.04nMrespectively).Displaysnonoticeablebindingtoanumberofotherreceptors,transportersorionchannels.Alsodisplaysanxiolyticandantidepressanteffectsinrodentmodels,withoutinducingbenzodiazepine-likeadverseeffects.

CompoundLibraries

AC5216isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	401.46
Formula	C₂₃H₂₃N₅O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	226954-04-7
PubChemID	6433109
InChIKey	NBMBIEOUVBHEBM-UHFFFAOYSA-N
Smiles	O=C(N1C)N(CC(N(CC)CC2=CC=CC=C2)=O)C3=C1C=NC(C4=CC=CC=C4)=N3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	40.15	100
	ethanol	4.01	10mMwithsonication

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight401.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.49mL	12.45mL	24.91mL
5mM	0.5mL	2.49mL	4.98mL
10mM	0.25mL	1.25mL	2.49mL
50mM	0.05mL	0.25mL	0.5mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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