CytochromeP450inhibitor.Inhibitssynthesisoftheeicosanoid20-hydroxyeicosatetraenoicacid(20-HETE).Reducesintimalhyperplasiaandvascularremodelingfollowingendothelialinjuryinratcarotidarteries.
M.Wt | 134.14 |
Formula | C6H6N4 |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 1614-12-6 |
PubChemID | 1367 |
InChIKey | JCXKHYLLVKZPKE-UHFFFAOYSA-N |
Smiles | NN2C1=CC=CC=C1N=N2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 13.41 | 100 | |
ethanol | 13.41 | 100 | |
water | 13.41 | 100 |
Thefollowingdataisbasedontheproductmolecularweight134.14.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 7.45mL | 37.27mL | 74.55mL |
5mM | 1.49mL | 7.45mL | 14.91mL |
10mM | 0.75mL | 3.73mL | 7.45mL |
50mM | 0.15mL | 0.75mL | 1.49mL |