ALDH1A1inhibitor(IC50=4.6μM;Ki=300nM).ExhibitsselectivityforALDH1A1overeightotherALDHisoforms.DisruptsspheroidformationandreducescellviABIlityofovariancancercellsinvitro.
| M.Wt | 431.57 |
| Formula | C21H25N3O3S2 |
| Storage | Storeat+4°C |
| Purity | ≥97%(HPLC) |
| CASNumber | 896795-60-1 |
| PubChemID | 5049161 |
| InChIKey | SKDRHRAYBYQVNU-UHFFFAOYSA-N |
| Smiles | O=C1N(CCCN2CCCC2)C(SCC(OCC)=O)=NC3=C1SC4=C3C=CC=C4 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 43.16 | 100 | |
| ethanol | 43.16 | 100 |
Thefollowingdataisbasedontheproductmolecularweight431.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.32mL | 11.59mL | 23.17mL |
| 5mM | 0.46mL | 2.32mL | 4.63mL |
| 10mM | 0.23mL | 1.16mL | 2.32mL |
| 50mM | 0.05mL | 0.23mL | 0.46mL |



