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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/A23187, free acid/1234/10/10 mg
产品编号:1234/10
市  场 价:¥2780.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/A23187, free acid/1234/10/10 mg
商品介绍
Description:Calciumionophore
AlternativeNames:Calcimycin
ChemicalName:5-(Methylamino)-2-[[2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CalciumionophorethatinducesCa2+-dependentcelldeathbyincreasingintracellularcalciumconcentration.PromotesintracelllularROSgenerationandplateletparticleformation(fragmentation)invitroandinvivo.Canbeusedtoinduceautophagyinmammaliancells.

TechnicalData

M.Wt523.63
FormulaC29H37N3O6
StorageDesiccateat+4°C
Purity≥98%(HPLC)
CASNumber52665-69-7
PubChemID11957499
InChIKeyHIYAVKIYRIFSCZ-CYEMHPAKSA-N
Smiles[H][C@@]1([C@H](C)C(C5=CC=CN5)=O)[C@H](C)C[C@@H](C)[C@@]2(O[C@H](CC3=NC(C(C(O)=O)=C(NC)C=C4)=C4O3)[C@H](C)CC2)O1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO26.1850

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight523.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.91mL9.55mL19.1mL
5mM0.38mL1.91mL3.82mL
10mM0.19mL0.95mL1.91mL
50mM0.04mL0.19mL0.38mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet