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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/A 939572/4845/10/10 mg
产品编号:4845/10
市  场 价:¥2980.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$149.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/A 939572/4845/10/10 mg
商品介绍
Description:PotentSCD-1inhibitor
ChemicalName:4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-piperidinecarboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentstearoyl-CoAdesaturase1(SCD1)inhibitor(IC50=0.4nM).SelectiveforSCD1overarangeofkinasesandhERGchannels.InhibitsproliferationofsquamouscellcarcinomaFaDucellsinvitro.Alsoinducescelldeathofundifferentiatedhumanembryonicstemcells(ESCs).Orallybioavailable.

CompoundLibraries

A939572isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt387.86
FormulaC20H22ClN3O3
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber1032229-3-6
PubChemID24905400
InChIKeyDPYTYQFYDLYWHZ-UHFFFAOYSA-N
SmilesO=C(NC3=CC(C(NC)=O)=CC=C3)N1CCC(OC2=C(Cl)C=CC=C2)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO38.79100
ethanol3.8810mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight387.86.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.58mL12.89mL25.78mL
5mM0.52mL2.58mL5.16mL
10mM0.26mL1.29mL2.58mL
50mM0.05mL0.26mL0.52mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet