Highaffinityα2-adrenoceptorantagonistandselective5-HTuptakeinhibitor(Kivaluesare2.01and3.77nMrespectively).DisplayslowaffinityatavarietyofstructurallyhomologousGPCRs.
| M.Wt | 445.57 |
| Formula | C23H27NO2.CH3SO3H |
| Storage | Desiccateat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 152148-64-6 |
| PubChemID | 10366248 |
| InChIKey | RKQPEIGWZATOHW-FYZYNONXSA-N |
| Smiles | COC1=C2C([C@H](CN(CCC3=CC(OC=C4)=C4C=C3)C)CCC2)=CC=C1.CS(=O)(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 44.56 | 100 | |
| water | 4.46 | 10 |
Thefollowingdataisbasedontheproductmolecularweight445.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.24mL | 11.22mL | 22.44mL |
| 5mM | 0.45mL | 2.24mL | 4.49mL |
| 10mM | 0.22mL | 1.12mL | 2.24mL |
| 50mM | 0.04mL | 0.22mL | 0.45mL |



