PotentinhibitoroftheLFA-1/ICAM-1interaction(IC50valuesare44and35nMinLFA-1/ICAM-1bindingandLFA-1-mediatedcelladhesionassaysrespectively).
| M.Wt | 453.55 |
| Formula | C24H27N3O4S |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 280749-17-9 |
| PubChemID | 9846729 |
| InChIKey | HTGGAYLWTDOFDK-PKNBQFBNSA-N |
| Smiles | O=C(C)N1CCN(C(/C=C/C2=CC([N+]([O-])=O)=C(SC3=CC=CC=C3C(C)C)C=C2)=O)CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 45.35 | 100 | |
| ethanol | 22.68 | 50 |
Thefollowingdataisbasedontheproductmolecularweight453.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.2mL | 11.02mL | 22.05mL |
| 5mM | 0.44mL | 2.2mL | 4.41mL |
| 10mM | 0.22mL | 1.1mL | 2.2mL |
| 50mM | 0.04mL | 0.22mL | 0.44mL |



