SelectiveinhibitorofE-selectinandICAM-1expression(IC50valuesare20,25and>1000nMforTNF-α-inducedE-selectin,ICAM-1andVCAM-1expressionrespectively).Effectiveinhibitorofcell-celladhesioninaninvitroflowexperiment.
A205804isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 300.39 |
Formula | C15H12N2OS2 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 251992-66-2 |
PubChemID | 9839311 |
InChIKey | QQGWEXFLMJGCAL-UHFFFAOYSA-N |
Smiles | CC1=CC=C(SC2=C3C=C(SC3=CN=C2)C(N)=O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 30.04 | 100 | |
ethanol | 3 | 10 |
Thefollowingdataisbasedontheproductmolecularweight300.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.33mL | 16.65mL | 33.29mL |
5mM | 0.67mL | 3.33mL | 6.66mL |
10mM | 0.33mL | 1.66mL | 3.33mL |
50mM | 0.07mL | 0.33mL | 0.67mL |