Highaffinityretinol-bindingprotein4(RBP4)ligand(Ki=8.3nM);non-retinoid.Selectiveagainstarangeofdifferentcellulartargets.Asefficaciousasfenretinide(Cat.No.1396)inthereductionofserumRBP4andretinol.Displacestransthyretin(TTR)fromRBP4-TTRcomplexes.
A1120isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 392.37 |
Formula | C20H19F3N2O3 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 1152782-19-8 |
PubChemID | 25138295 |
InChIKey | MEAQCLPMSVEOQF-UHFFFAOYSA-N |
Smiles | O=C(NC3=C(C(O)=O)C=CC=C3)N1CCC(C2=C(C(F)(F)F)C=CC=C2)CC1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 39.24 | 100 | |
ethanol | 9.81 | 25 |
Thefollowingdataisbasedontheproductmolecularweight392.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.55mL | 12.74mL | 25.49mL |
5mM | 0.51mL | 2.55mL | 5.1mL |
10mM | 0.25mL | 1.27mL | 2.55mL |
50mM | 0.05mL | 0.25mL | 0.51mL |