Antitumoragent;selectiveforcellsexpressingoncogenicRAS.AlsoFerroptosisactivator;inducesoxidative,non-apoptoticcelldeathintumorsbymodulatingmitochondrialvoltage-dependentanionchannels(VDAC).Cellpermeable.
| M.Wt | 547.04 |
| Formula | C30H31ClN4O4 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 571203-78-6 |
| PubChemID | 11214940 |
| InChIKey | BKQFRNYHFIQEKN-UHFFFAOYSA-N |
| Smiles | O=C2C1=CC=CC=C1N=C(C(N4CCN(C(COC5=CC=C(Cl)C=C5)=O)CC4)C)N2C3=C(OCC)C=CC=C3 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 10.94 | 20 |
Thefollowingdataisbasedontheproductmolecularweight547.04.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.83mL | 9.14mL | 18.28mL |
| 5mM | 0.37mL | 1.83mL | 3.66mL |
| 10mM | 0.18mL | 0.91mL | 1.83mL |
| 50mM | 0.04mL | 0.18mL | 0.37mL |



