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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Erastin/5449/10/10 mg
产品编号:5449/10
市  场 价:¥3900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$195.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Erastin/5449/10/10 mg
商品介绍
Description:MitochondriaVDACmodulator;alsoFerroptosisactivator
ChemicalName:2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antitumoragent;selectiveforcellsexpressingoncogenicRAS.AlsoFerroptosisactivator;inducesoxidative,non-apoptoticcelldeathintumorsbymodulatingmitochondrialvoltage-dependentanionchannels(VDAC).Cellpermeable.

TechnicalData

M.Wt547.04
FormulaC30H31ClN4O4
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber571203-78-6
PubChemID11214940
InChIKeyBKQFRNYHFIQEKN-UHFFFAOYSA-N
SmilesO=C2C1=CC=CC=C1N=C(C(N4CCN(C(COC5=CC=C(Cl)C=C5)=O)CC4)C)N2C3=C(OCC)C=CC=C3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO10.9420

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight547.04.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.83mL9.14mL18.28mL
5mM0.37mL1.83mL3.66mL
10mM0.18mL0.91mL1.83mL
50mM0.04mL0.18mL0.37mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet