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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Entecavir/6234/50/50 mg
产品编号:6234/50
市  场 价:¥4180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$209.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Entecavir/6234/50/50 mg
商品介绍
Description:PotentandselectivehepatitisBvirusinhibitor
AlternativeNames:BMS200475,SQ34676
ChemicalName:2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivehepatitisBvirusreversetranscriptaseinhibitor(EC50=3nM);guanineanalog.InhibitshepatitisBvirusreplicationinHepG2.2.15cells.DisplaysselectivelyoverHCMV,HSV-1,VZV,HIVandinfluenza(EC50valuesare15,32,30-60,>10and>80μMrespectively).Orallybioavailable.

TechnicalData

M.Wt277.28
FormulaC12H15N5O3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber142217-69-4
PubChemID153941
InChIKeyQDGZDCVAUDNJFG-FXQIFTODSA-N
SmilesO=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)C3=C)C=N2)NC(N)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO27.73100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight277.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.61mL18.03mL36.06mL
5mM0.72mL3.61mL7.21mL
10mM0.36mL1.8mL3.61mL
50mM0.07mL0.36mL0.72mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet