Phosphodiesteraseinhibitor,selectiveforPDE3and4(IC50valuesare0.5and0.8μMrespectively).AlsoavailableaspartofthePhosphodiesteraseInhibitorTocriset™.
ZardaverineisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 268.22 |
| Formula | C12H10F2N2O3 |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 101975-10-4 |
| PubChemID | 5723 |
| InChIKey | HJMQDJPMQIHLPB-UHFFFAOYSA-N |
| Smiles | COC1=C(OC(F)F)C=CC(=C1)C1=NNC(=O)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solubility | Solubleto100mMinDMSO |
Thefollowingdataisbasedontheproductmolecularweight268.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.73mL | 18.64mL | 37.28mL |
| 5mM | 0.75mL | 3.73mL | 7.46mL |
| 10mM | 0.37mL | 1.86mL | 3.73mL |
| 50mM | 0.07mL | 0.37mL | 0.75mL |



