Piezo1channelactivator.Slowstheinactivationphaseoftransientcurrents,sensitizesPiezo1toactivationbypressure,andpartiallyactivateschannelsintheabsenceofexternalpressure,inHEKcellsexpressingPiezo1channels.
Yoda1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 355.27 |
| Formula | C13H8Cl2N4S2 |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 448947-81-7 |
| PubChemID | 2746822 |
| InChIKey | BQNXBSYSQXSXPT-UHFFFAOYSA-N |
| Smiles | ClC1=C(CSC2=NN=C(C3=NC=CN=C3)S2)C(Cl)=CC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 17.76 | 50 |
Thefollowingdataisbasedontheproductmolecularweight355.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.81mL | 14.07mL | 28.15mL |
| 5mM | 0.56mL | 2.81mL | 5.63mL |
| 10mM | 0.28mL | 1.41mL | 2.81mL |
| 50mM | 0.06mL | 0.28mL | 0.56mL |



