OrallyactivePDE4inhibitor(IC50=2.2nM).Lowemetogenicactivity,suggestedtobeduetopoorbrainpenetration.
YM976isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 313.79 |
Formula | C17H16ClN3O |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 191219-80-4 |
PubChemID | 6604918 |
InChIKey | MNHXYNNKDDXKNP-UHFFFAOYSA-N |
Smiles | CCN1C(=O)N=C(C2=CC=CC(Cl)=C2)C2=C1N=C(CC)C=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 31.38 | 100 | |
ethanol | 31.38 | 100 |
Thefollowingdataisbasedontheproductmolecularweight313.79.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.19mL | 15.93mL | 31.87mL |
5mM | 0.64mL | 3.19mL | 6.37mL |
10mM | 0.32mL | 1.59mL | 3.19mL |
50mM | 0.06mL | 0.32mL | 0.64mL |