OrallyactivePDE4inhibitor(IC50=2.2nM).Lowemetogenicactivity,suggestedtobeduetopoorbrainpenetration.
YM976isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 313.79 |
| Formula | C17H16ClN3O |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 191219-80-4 |
| PubChemID | 6604918 |
| InChIKey | MNHXYNNKDDXKNP-UHFFFAOYSA-N |
| Smiles | CCN1C(=O)N=C(C2=CC=CC(Cl)=C2)C2=C1N=C(CC)C=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 31.38 | 100 | |
| ethanol | 31.38 | 100 |
Thefollowingdataisbasedontheproductmolecularweight313.79.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.19mL | 15.93mL | 31.87mL |
| 5mM | 0.64mL | 3.19mL | 6.37mL |
| 10mM | 0.32mL | 1.59mL | 3.19mL |
| 50mM | 0.06mL | 0.32mL | 0.64mL |



