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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/YM 976/1821/10/10 mg
产品编号:1821/10
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/YM 976/1821/10/10 mg
商品介绍
Description:PDE4inhibitor
ChemicalName:4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

OrallyactivePDE4inhibitor(IC50=2.2nM).Lowemetogenicactivity,suggestedtobeduetopoorbrainpenetration.

CompoundLibraries

YM976isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt313.79
FormulaC17H16ClN3O
StorageStoreatRT
Purity≥98%(HPLC)
CASNumber191219-80-4
PubChemID6604918
InChIKeyMNHXYNNKDDXKNP-UHFFFAOYSA-N
SmilesCCN1C(=O)N=C(C2=CC=CC(Cl)=C2)C2=C1N=C(CC)C=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO31.38100
ethanol31.38100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight313.79.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.19mL15.93mL31.87mL
5mM0.64mL3.19mL6.37mL
10mM0.32mL1.59mL3.19mL
50mM0.06mL0.32mL0.64mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet