InhibitorofRNAHelicaseA(RHA)bindingtotheoncogenictransciptionfactorEWS-FLI1.InhibitsEwing'ssarcomafamilytumor(ESFT)cellgrowth;inducesapoptosis.
YK4-279isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 366.2 |
Formula | C17H13Cl2NO4 |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 1037184-44-3 |
PubChemID | 44632017 |
InChIKey | HLXSCTYHLQHQDJ-UHFFFAOYSA-N |
Smiles | O=C2NC1=C(Cl)C=CC(Cl)=C1C(CC(C3=CC=C(OC)C=C3)=O)2O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 36.62 | 100 |
Thefollowingdataisbasedontheproductmolecularweight366.2.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.73mL | 13.65mL | 27.31mL |
5mM | 0.55mL | 2.73mL | 5.46mL |
10mM | 0.27mL | 1.37mL | 2.73mL |
50mM | 0.05mL | 0.27mL | 0.55mL |