GPR35agonist(EC50=32nMinDMRassays).Alsodisplayspartialagonistactivityinaβ-arrestintranslocationassay(EC50=10.2μM).
| M.Wt | 330.17 |
| Formula | C16H9Cl2N3O |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 383124-82-1 |
| PubChemID | 12138435 |
| InChIKey | RSWZFAPYKOARNG-UHFFFAOYSA-N |
| Smiles | CC(C(C2=CC=C(Cl)C(Cl)=C2)(C)O1)=C(C#N)/C1=C(C#N)C#N |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.02 | 100 |
Thefollowingdataisbasedontheproductmolecularweight330.17.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.03mL | 15.14mL | 30.29mL |
| 5mM | 0.61mL | 3.03mL | 6.06mL |
| 10mM | 0.3mL | 1.51mL | 3.03mL |
| 50mM | 0.06mL | 0.3mL | 0.61mL |



