请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Y 134/2676/10/10 mg
产品编号:2676/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Y 134/2676/10/10 mg
商品介绍
Description:Selectiveestrogenreceptormodulator(SERM),selectiveforERα
ChemicalName:[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[4-(1-methylethyl)-1-piperazinyl]phenyl]methanone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveestrogenreceptormodulator(SERM)thatdisplaysselectivityforERαoverERβ(Kivaluesare0.09and11.31nMrespectively)andnocross-reactivitywithmineralocorticoid,glucocorticoid,androgenandprogesteronereceptors.ActsasanagoNISTintheboneandantagonistinreproductivetissue.Suppressesestrogen-stimulatedproliferationofER-positivehumanbreastcancerMCF-7andT47Dcells.

CompoundLibraries

Y134isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt472.6
FormulaC28H28N2O3S
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber849662-80-2
PubChemID11784736
InChIKeyLQEOPHGPHCWOAC-UHFFFAOYSA-N
SmilesCC(C)N1CCN(CC1)C1=CC=C(C=C1)C(=O)C1=C(SC2=CC(O)=CC=C12)C1=CC=C(O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO47.26100
ethanol47.26100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight472.6.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.12mL10.58mL21.16mL
5mM0.42mL2.12mL4.23mL
10mM0.21mL1.06mL2.12mL
50mM0.04mL0.21mL0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet