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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Wiskostatin/4434/50/50 mg
产品编号:4434/50
市  场 价:¥16500.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$825.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Wiskostatin/4434/50/50 mg
商品介绍
Description:N-WASPinhibitor;inhibitsArp2/3activation
ChemicalName:3,6-Dibromo-α-[(dimethylamino)methyl]-9H-cabazole-9-ethanol
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofneuralWiskott-Aldrichsyndromeprotein(N-WASP)activity.InteractswiththeregulatoryGTPase-bindingdomainofN-WASP;inhibitsactivationofArp2/3complexbymaintainingN-WASPinaninactiveconformation.AlsoinhibitsPIP2-inducedactinpolymerization(EC50~4μM).

CompoundLibraries

WiskostatinisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt426.15
FormulaC17H18Br2N2O
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber253449-04-6
PubChemID2775510
InChIKeyXUBJEDZHBUPBKL-UHFFFAOYSA-N
SmilesBrC(C=C3)=CC1=C3N(CC(O)CN(C)C)C2=C1C=C(Br)C=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO42.62100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight426.15.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.35mL11.73mL23.47mL
5mM0.47mL2.35mL4.69mL
10mM0.23mL1.17mL2.35mL
50mM0.05mL0.23mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet