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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/WEB 2086/2339/1/1 mg
产品编号:2339/1
市  场 价:¥2300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$115.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/WEB 2086/2339/1/1 mg
商品介绍
Description:PotentPAFreceptorantagoNIST
AlternativeNames:Apafant
ChemicalName:4-[3-[4[(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a]diazepin-2-yl]-1-oxopropyl]morpholine
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,selectiveplatelet-activatingfactor(PAF)receptorantagonist(Ki=16.3nM).Displaysanti-inflammatory,antiangiogenicandanticanceractivity.InhibitsgrowthandproliferationofMCF-7breastcancercells.

CompoundLibraries

WEB2086isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt455.96
FormulaC22H22N5O2SCl
StorageDesiccateat+4°C
Purity≥99%(HPLC)
CASNumber105219-56-5
PubChemID65889
InChIKeyJGPJQFOROWSRRS-UHFFFAOYSA-N
SmilesCC1=NN=C2CN=C(C3=C(SC(CCC(=O)N4CCOCC4)=C3)N12)C1=CC=CC=C1Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO45.6100
ethanol45.6100mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight455.96.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.19mL10.97mL21.93mL
5mM0.44mL2.19mL4.39mL
10mM0.22mL1.1mL2.19mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet