SecretedFrizzled-RelatedProtein-1(sFRP-1)inhibitor(IC50=0.65μM);preventssFRP-1frominteractingwithWntandthusincreasesWntsignaling.Increasestotalboneareainamurinecalvarialorgancultureassay.
WAY316606hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 484.94 |
Formula | C18H19F3N2O4S2.HCl |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
PubChemID | 25186563 |
InChIKey | YLOYHLUHXQJNGO-UHFFFAOYSA-N |
Smiles | O=S(C1=CC=C(C(F)(F)F)C(S(NC3CCNCC3)(=O)=O)=C1)(C2=CC=CC=C2)=O.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 9.7 | 20 |
Thefollowingdataisbasedontheproductmolecularweight484.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.06mL | 10.31mL | 20.62mL |
5mM | 0.41mL | 2.06mL | 4.12mL |
10mM | 0.21mL | 1.03mL | 2.06mL |
50mM | 0.04mL | 0.21mL | 0.41mL |