请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/W 54011/5455/50/50 mg
产品编号:5455/50
市  场 价:¥20900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$1045.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/W 54011/5455/50/50 mg
商品介绍
Description:HighaffinityC5areceptorantagoNIST
ChemicalName:N-[[4-(Dimethylamino)phenyl]methyl]-1,2,3,4-tetrahydro-7-methoxy-N-[4-(1-methylethyl)phenyl]-1-naphthalenecarboxamidehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityC5areceptorantagonist(Ki=2.2nM).InhibitsC5a-inducedgenerationofreactivesuperoxidespecies,chemotaxisandintracellularCa2+mobilizationinhumanneutrophils(IC50valuesare1.6,2.7and3.1nM,respectively).

CompoundLibraries

W54011isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt493.08
FormulaC30H36N2O2.HCl
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber405098-33-1
PubChemID5311121
InChIKeyUKBJWRMNGCDKNL-UHFFFAOYSA-N
SmilesCC(C)C1=CC=C(N(CC2=CC=C(N(C)C)C=C2)C(C3C(C=C(OC)C=C4)=C4CCC3)=O)C=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO24.6550
ethanol4.9310mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight493.08.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.03mL10.14mL20.28mL
5mM0.41mL2.03mL4.06mL
10mM0.2mL1.01mL2.03mL
50mM0.04mL0.2mL0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet