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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/(-)-Xestospongin C/1280/10U/10 ug
产品编号:1280/10U
市  场 价:¥3980.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/(-)-Xestospongin C/1280/10U/10 ug
商品介绍
Description:ReportedinhibitorofIP3-dependentCa2+release
AlternativeNames:XeC
ChemicalName:(1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

ReportedinhibitorofIP3-dependentCa2+release.Inhibitsbradykinin-inducedCa2+releaseinPC12cellsandattenuatesPHP-inducedIL-2productioninJurkatTcells.Exhibitsnoeffectonryanodinereceptor-mediatedCa2+releaseinPC12cells.DoesnotinteractwiththeIP3bindingsite.RecentlyshowntobeanineffectiveantagoNISTofIP3-evokedCa2+releaseinIP3receptorexpressingDT40cells.Cellpermeable.

TechnicalData

M.Wt446.71
FormulaC28H50N2O2
StorageDesiccateat-20°C
CASNumber88903-69-9
PubChemID9846431
InChIKeyPQYOPBRFUUEHRC-HCKQMYSWSA-N
Smiles[H][C@]12[C@@H](CCCCCC[C@@H]3CCN(CCC[C@H]4CCCCCC5)[C@@]4([H])O3)CCCN1CC[C@@H]5O2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO0.892
ethanol0.892

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight446.71.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.24mL11.19mL22.39mL
5mM0.45mL2.24mL4.48mL
10mM0.22mL1.12mL2.24mL
50mM0.04mL0.22mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet