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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Xanthohumol/4686/10/10 mg
产品编号:4686/10
市  场 价:¥3580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$179.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Xanthohumol/4686/10/10 mg
商品介绍
Description:p97ATPase(VCP)inhibitor
ChemicalName:(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

p97ATPase(VCP)inhibitor.BindstotheNdomainofp97,impairingautophagosomefunctionandmaturation.Inhibitsproliferationandinducesapoptosisinavarietyofhumancancercelllines.AlsoinhibitsDGATinratlivermicrosomes(IC50=50.3μM).

TechnicalData

M.Wt354.4
FormulaC21H22O5
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber6754-58-1
PubChemID639665
InChIKeyORXQGKIUCDPEAJ-YRNVUSSQSA-N
SmilesOC1=C(C(/C=C/C2=CC=C(O)C=C2)=O)C(OC)=CC(O)=C1C/C=C(C)/C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO35.44100
ethanol35.44100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight354.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.82mL14.11mL28.22mL
5mM0.56mL2.82mL5.64mL
10mM0.28mL1.41mL2.82mL
50mM0.06mL0.28mL0.56mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet