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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Voglibose/3596/50/50 mg
产品编号:3596/50
市  场 价:¥14100.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$705.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Voglibose/3596/50/50 mg
商品介绍
Description:Orallyactiveα-glucosidaseinhibitor
ChemicalName:3,4-Dideoxy-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-C-(hydroxymethyl)-D-epi-inositol
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Orallyactiveα-glucosidaseinhibitor(IC50valuesare3.9and6.4nMatsucraseandmaltaserespectively).Increasesglucagon-likepeptide1(GLP-1)secretionanddecreasesfoodconsumptioninob/obmice,andreducesplasmaconcentrationsofglucose,triglyceridesandinsulininWistarfattyrats.Exhibitsantidiabeticandantiobesityactivityinvivo.

CompoundLibraries

VogliboseisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt267.28
FormulaC10H21NO7
StorageStoreat-20°C
CASNumber83480-29-9
PubChemID444020
InChIKeyFZNCGRZWXLXZSZ-CIQUZCHMSA-N
SmilesO[C@@H]1[C@](CO)(O)C[C@H](NC(CO)CO)[C@H](O)[C@H]1O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO20.0575
water26.73100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight267.28.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.74mL18.71mL37.41mL
5mM0.75mL3.74mL7.48mL
10mM0.37mL1.87mL3.74mL
50mM0.07mL0.37mL0.75mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet