Dualserotonin/noradrenalinre-uptakeinhibitorthatdisplays~30-foldhigheraffinityforSERTthanNET(Kivaluesare82and2480nMrespectively).Antidepressant;increasesswimmingandclimbingbehaviorintheforced-swimtestinrats.
VenlafaxinehydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 313.86 |
Formula | C17H27NO2.HCl |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 99300-78-4 |
PubChemID | 62923 |
InChIKey | QYRYFNHXARDNFZ-UHFFFAOYSA-N |
Smiles | OC2(CCCCC2)C(CN(C)C)C1=CC=C(OC)C=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 15.69 | 50 | |
ethanol | 31.39 | 100 | |
water | 31.39 | 100 |
Thefollowingdataisbasedontheproductmolecularweight313.86.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.19mL | 15.93mL | 31.86mL |
5mM | 0.64mL | 3.19mL | 6.37mL |
10mM | 0.32mL | 1.59mL | 3.19mL |
50mM | 0.06mL | 0.32mL | 0.64mL |